LNP023 (Synonyms: LNP023) |
| Catalog No.GC36472 |
LNP023 (LNP023) est un inhibiteur du facteur B de première classe, biodisponible par voie orale, très puissant et hautement sélectif avec une valeur IC50 de 10 nM.
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Cas No.: 1644670-37-0
Sample solution is provided at 25 µL, 10mM.
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LNP023 is a highly potent factor B (FB) inhibitor with an IC50 value of 10 nM. LNP023 shows direct, reversible, and high-affinity binding to human FB (KD=7.9 nM)[1].
[1]. Schubart A, et al. Small-molecule factor B inhibitor for the treatment of complement-mediated diseases. Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7926-7931.
Average Rating: 5 (Based on Reviews and 15 reference(s) in Google Scholar.)
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