Oglemilast |
Catalog No.GC36793 |
L'oglémilast (GRC 3886) est un inhibiteur de la phosphodiestérase-4 (PDE4) puissant et actif par voie orale avec une IC50 de 0,5 nM pour la PDE4D3.
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Cas No.: 778576-62-8
Sample solution is provided at 25 µL, 10mM.
Oglemilast(GRC3886) is a potent PDE4 inhibitor, under clinical studies in the treatment of allergen-induced asthma.IC50 value:Target: PDE4
[1]. Giembycz MA. Can the anti-inflammatory potential of PDE4 inhibitors be realized: guarded optimism or wishful thinking• Br J Pharmacol. 2008 Oct;155(3):288-90. [2]. Study of Oglemilast for the Prevention of Asthma. [3]. Study To Assess Efficacy and Safety of Oglemilast in Patients With Chronic Obstructive Pulmonary Disease (COPD) [4]. Study of Oglemilast for the Treatment of Asthma
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