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Tuberculosis inhibitor 1

Catalog No.GC37834

L'inhibiteur de la tuberculose 1 est un inhibiteur de croissance puissant et non cytotoxique de Trypanosoma brucei avec une CE50 de 5 nM.

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Tuberculosis inhibitor 1 Chemical Structure

Cas No.: 2230810-28-1

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Tuberculosis inhibitor 1 is a potent and non-cytotoxic trypanosoma brucei growth inhibitor with an EC50 of 5 nM[1]. EC50: 5 nM (Trypanosoma brucei)[1]

Tuberculosis inhibitor 1 is selective over other parasites, such as Trypanosoma cruzi and Plasmodium falciparum (T. cruzi EC50 8120 nM, P. falciparum EC50 3624 nM)[1].

[1]. Ferrigno F, et al. Discovery of 2-(1H-imidazo-2-yl)piperazines as a new class of potent and non-cytotoxic inhibitorsof Trypanosoma brucei growth in vitro. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3689-3692.

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Average Rating: 5 ★★★★★ (Based on Reviews and 8 reference(s) in Google Scholar.)

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