[Sar9,Met(O2)11]-Substance P TFA |
Catalog No.GC38013 |
[Sar9,Met(O2)11]-Substance P TFA est un agoniste sélectif des récepteurs de la tachykinine NK1.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2828433-10-7
Sample solution is provided at 25 µL, 10mM.
[Sar9,Met(O2)11]-Substance P TFA is a tachykinin NK1 receptor selective agonist.
[Sar9,Met(O2)11]-Substance P and septide (10-100 pmol per rat, i.c.v.) are equipotent in increasing mean arterial blood pressure (MAP) and heart rate (HR), yet they have dissimilar time-course. Both agonists increase dose-dependently face washing and sniffing while [Sar9,Met(O2)11]-Substance P is the sole to produce grooming[1].
[1]. Cellier E, et al. Characterization of central and peripheral effects of septide with the use of five tachykinin NK1 receptor antagonists in the rat. Br J Pharmacol. 1999 Jun;127(3):717-28.
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