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[Sar9,Met(O2)11]-Substance P TFA Catalog No.GC38013

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Sample solution is provided at 25 µL, 10mM.

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Chemical Properties

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Formula C66H101N18F3O17S M.Wt 1507.68
Solubility H2O: 100 mg/mL (66.33 mM) Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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[Sar9,Met(O2)11]-Substance P TFA is a tachykinin NK1 receptor selective agonist.

[Sar9,Met(O2)11]-Substance P and septide (10-100 pmol per rat, i.c.v.) are equipotent in increasing mean arterial blood pressure (MAP) and heart rate (HR), yet they have dissimilar time-course. Both agonists increase dose-dependently face washing and sniffing while [Sar9,Met(O2)11]-Substance P is the sole to produce grooming[1].

[1]. Cellier E, et al. Characterization of central and peripheral effects of septide with the use of five tachykinin NK1 receptor antagonists in the rat. Br J Pharmacol. 1999 Jun;127(3):717-28.