Glucagon Receptor Antagonist I (Synonyms: GCGR Antagonist I) |
| Catalog No.GC43765 |
Glucagon receptor antagonist I is a competitive antagonist of the glucagon receptor (GCGR; IC50 = 181 nM).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 438618-32-7
Sample solution is provided at 25 µL, 10mM.
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Glucagon receptor antagonist I is a competitive antagonist of the glucagon receptor (GCGR; IC50 = 181 nM). It blocks glucagon-induced glycogenolysis in primary human hepatocytes and isolated liver. Glucagon receptor antagonist I, at 50 mg/kg, reduces the increase in glucose levels observed after intraperitoneal administration of glucagon in humanized mice. Glucagon receptor antagonist inactive control does not prevent glucagon-mediated actions.
Average Rating: 5 (Based on Reviews and 32 reference(s) in Google Scholar.)
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