Halofantrine hydrochloride (SKF-102886) (Synonyms: (±)-Halofantrine, SKF 102886, WR 171669) |
| Catalog No.GC32377 |
Le chlorhydrate d'halofantrine (SKF-102886) (SKF-102886) est un bloqueur du courant potassique redresseur retardé via l'inhibition du canal HERG (human-ether-a-go-go-related gene) et un puissant composé antipaludéen.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 36167-63-2
Sample solution is provided at 25 µL, 10mM.
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Halofantrine hydrochloride (SKF-102886) is a blocker of delayed rectifier potassium current via the inhibition of human-ether-a-go-go-related gene (HERG) channel and a potent antimalarial compound[1][2].
[1]. Krishna S, et al. Pharmacokinetics, efficacy and toxicity of parenteral halofantrine in uncomplicated malaria. Br J Clin Pharmacol. 1993 Dec;36(6):585-91. [2]. Tie, H., et al., Inhibition of HERG potassium channels by the antimalarial agent halofantrine. Br. J. Pharmacol. 130, 1967-1975, (2000) Traebert.
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