>>Signaling Pathways>> Microbiology & Virology>> Parasite>>Halofantrine hydrochloride (SKF-102886)

Halofantrine hydrochloride (SKF-102886) (Synonyms: (±)-Halofantrine, SKF 102886, WR 171669)

Catalog No.GC32377

할로판트린 염산염(SKF-102886)(SKF-102886)은 HERG(human-ether-a-go-go-related gene) 채널과 강력한 항말라리아 화합물의 억제를 통해 지연된 정류기 칼륨 전류의 차단제입니다.

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Halofantrine hydrochloride (SKF-102886) Chemical Structure

Cas No.: 36167-63-2

Size 가격 재고 수량
10mM (in 1mL DMSO)
US$141.00
재고 있음
1mg
US$43.00
재고 있음
5mg
US$119.00
재고 있음
10mg
US$211.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Halofantrine hydrochloride (SKF-102886) is a blocker of delayed rectifier potassium current via the inhibition of human-ether-a-go-go-related gene (HERG) channel and a potent antimalarial compound[1][2].

[1]. Krishna S, et al. Pharmacokinetics, efficacy and toxicity of parenteral halofantrine in uncomplicated malaria. Br J Clin Pharmacol. 1993 Dec;36(6):585-91. [2]. Tie, H., et al., Inhibition of HERG potassium channels by the antimalarial agent halofantrine. Br. J. Pharmacol. 130, 1967-1975, (2000) Traebert.

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Average Rating: 5 ★★★★★ (Based on Reviews and 6 reference(s) in Google Scholar.)

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