Halofantrine hydrochloride (SKF-102886) (Synonyms: (±)-Halofantrine, SKF 102886, WR 171669) |
Catalog No.GC32377 |
할로판트린 염산염(SKF-102886)(SKF-102886)은 HERG(human-ether-a-go-go-related gene) 채널과 강력한 항말라리아 화합물의 억제를 통해 지연된 정류기 칼륨 전류의 차단제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 36167-63-2
Sample solution is provided at 25 µL, 10mM.
Halofantrine hydrochloride (SKF-102886) is a blocker of delayed rectifier potassium current via the inhibition of human-ether-a-go-go-related gene (HERG) channel and a potent antimalarial compound[1][2].
[1]. Krishna S, et al. Pharmacokinetics, efficacy and toxicity of parenteral halofantrine in uncomplicated malaria. Br J Clin Pharmacol. 1993 Dec;36(6):585-91. [2]. Tie, H., et al., Inhibition of HERG potassium channels by the antimalarial agent halofantrine. Br. J. Pharmacol. 130, 1967-1975, (2000) Traebert.
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