IDO1/2-IN-1 hydrochloride |
| Catalog No.GC65499 |
Le chlorhydrate d'IDO1/2-IN-1 (composé 4t) est le premier puissant inhibiteur double IDO1/IDO2 avec des IC50 de 28 nM et 144 nM pour IDO1 et IDO2, respectivement. Le chlorhydrate d'IDO1/2-IN-1 présente des activités antitumorales. Oralement actif.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2310286-60-1
Sample solution is provided at 25 µL, 10mM.
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IDO1/2-IN-1 hydrochloride (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively. IDO1/2-IN-1 hydrochloride exhibits antitumor activies. Orally active[1].
[1]. He X, et al. Discovery of the First Potent IDO1/IDO2 Dual Inhibitors: A Promising Strategy for Cancer Immunotherapy. J Med Chem. 2021;64(24):17950-17968.
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