IDO1/2-IN-1 hydrochloride |
| Catalog No.GC65499 |
IDO1/2-IN-1 염산염(화합물 4t)은 IDO1 및 IDO2에 대해 각각 28nM 및 144nM의 IC50을 갖는 최초의 강력한 IDO1/IDO2 이중 억제제입니다. IDO1/2-IN-1 염산염은 항종양 활성을 나타냅니다. 구두로 활동적입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2310286-60-1
Sample solution is provided at 25 µL, 10mM.
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IDO1/2-IN-1 hydrochloride (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively. IDO1/2-IN-1 hydrochloride exhibits antitumor activies. Orally active[1].
[1]. He X, et al. Discovery of the First Potent IDO1/IDO2 Dual Inhibitors: A Promising Strategy for Cancer Immunotherapy. J Med Chem. 2021;64(24):17950-17968.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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