JF-NP-26 |
| Catalog No.GC50497 |
JF-NP-26, un dérivé photocagé inactif du raseglurant, est le premier modulateur allostérique négatif du récepteur mGlu5 en cage.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2341841-03-8
Sample solution is provided at 25 µL, 10mM.
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Caged Raseglurant . Releases raseglurant upon exposure to 405 nm (violet) light. Inhibits the effects of Quisqualate in cultured neurons when exposed to 405 nm light. Exhibits analgesic activity in pain models in vivo on photoactivation. Quantum yield = 0.18.
Font et al (2017) Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator. eLIFE 6 e23545 PMID:28395733
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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