JF-NP-26 |
| Catalog No.GC50497 |
라세글루란트의 비활성 광케이지드 유도체인 JF-NP-26은 최초의 케이지형 mGlu5 수용체 음성 알로스테릭 조절제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2341841-03-8
Sample solution is provided at 25 µL, 10mM.
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Caged Raseglurant . Releases raseglurant upon exposure to 405 nm (violet) light. Inhibits the effects of Quisqualate in cultured neurons when exposed to 405 nm light. Exhibits analgesic activity in pain models in vivo on photoactivation. Quantum yield = 0.18.
Font et al (2017) Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator. eLIFE 6 e23545 PMID:28395733
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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