Lenalidomide-C5-amido-Boc |
| Catalog No.GC63474 |
Le lénalidomide-C5-amido-Boc est le ligand Cereblon À base de lénalidomide utilisé dans le recrutement de la protéine CRBN. Le lénalidomide-C5-amido-Boc peut être connecté au ligand de la protéine par un lieur pour former PROTAC.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2138441-25-3
Sample solution is provided at 25 µL, 10mM.
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Lenalidomide-C5-amido-Boc is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-amido-Boc can be connected to the ligand for protein by a linker to form PROTAC[1].
[1]. Wang, Shaomeng, et al. Preparation of phthalimide-based compounds as monofunctional intermediates for ligand-dependent target protein degradation. World Intellectual Property Organization, WO2017176958 A1 2017-10-12.
[2]. Robbins, Daniel, et al. WBifunctional compounds for degrading BTK via ubiquitin proteasome pathway. World Intellectual Property Organization, WO2021091575 A1 2021-05-14.
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