Lithocholic Acid 3-sulfate (sodium salt) (Synonyms: Lithocholate 3-sulfate) |
| Catalog No.GC44077 |
Lithocholic acid 3-sulfate is a metabolite of the secondary bile acid lithocholic acid.
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Cas No.: 64936-81-8
Sample solution is provided at 25 µL, 10mM.
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Lithocholic acid 3-sulfate is a metabolite of the secondary bile acid lithocholic acid.[1] It is water soluble and the primary form of lithocholic acid in the bile duct. Lithocholic acid 3-sulfate forms a complex with calcium in vitro.[2] Biliary secretion of lithocholic acid 3-sulfate is increased in a rat model of diabetes induced by streptozotocin.[3]
Reference:
[1]. Borriello, S.P., and Owen, R.W. The metabolism of lithocholic acid and lithocholic acid-3-α-sulfate by human fecal bacteria. Lipids 17(7), 477-482 (1982).
[2]. Oelberg, D.G., Dubinsky, W.P., Adcock, E.W., et al. Calcium binding by lithocholic acid derivatives. Am. J. Physiol. 247(1 Pt 1), G112-G115 (1984).
[3]. Kirkpatrick, R.B., and Kraft, B.G. Effect of streptozotocin-induced diabetes on bile acid sulfation in male rat liver. Am. J. Physiol. 247(3 Pt 1), G226-G230 (1984).
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