NVS-ZP7-4 |
| Catalog No.GC34323 |
NVS-ZP7-4 est un inhibiteur du transporteur de zinc SLC39A7 (ZIP7) qui est également le premier outil chimique rapporté pour sonder l'impact de la modulation des niveaux de zinc ER et étudier ZIP7 en tant que nouveau nœud médicamenteux dans la voie Notch.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2349367-89-9
Sample solution is provided at 25 µL, 10mM.
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NVS-ZP7-4 is a Zinc transporter SLC39A7 (ZIP7) inhibitor that is also the first reported chemical tool to probe the impact of modulating ER zinc levels and investigate ZIP7 as a novel druggable node in the Notch pathway.
NVS-ZP7-4 increases ER zinc levels, suggesting functional modulation of ZIP7[1].
[1]. Nolin E, et al. Discovery of a ZIP7 inhibitor from a Notch pathway screen. Nat Chem Biol. 2019 Feb;15(2):179-188.
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