PF 04418948 |
| Catalog No.GC11067 |
PF 04418948 est un antagoniste des récepteurs de la prostaglandine EP2 actif par voie orale, puissant et sélectif avec une IC50 de 16 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1078166-57-0
Sample solution is provided at 25 µL, 10mM.
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PF-04418948 is an orally active, potent and selective prostaglandin EP2 receptor antagonist with an IC50 of 16 nM.
References:
[1]. af Forselles KJ, et al. In vitro and in vivo characterization of PF-04418948, a novel, potent and selective prostaglandin EP2 receptor antagonist. Br J Pharmacol. 2011 Dec;164(7):1847-1856.
[2]. Birrell MA, et al. Selectivity profiling of the novel EP2 receptor antagonist, PF-04418948, in functional bioassay systems: atypical affinity at the guinea pig EP2 receptor. Br J Pharmacol. 2013 Jan;168(1):129-138.
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