Pterosin B |
| Catalog No.GC39148 |
La ptérosine B, une indanone trouvée dans la fougère aigle (Pteridium aquilinum), est un inhibiteur de la signalisation de la kinase 3 inductible par le sel (Sik3).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 34175-96-7
Sample solution is provided at 25 µL, 10mM.
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Pterosin B, a indanone found in bracken fern (Pteridium aquilinum), is an inhibitor of salt-inducible kinase 3 (Sik3) signaling. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3[1][2].
[1]. Hannah R.Dexter, et al. A concise stereoselective synthesis of pterosin B. Tetrahedron Letters, Volume 59, Issue 49, 5 December 2018, Pages 4323-4325. [2]. Yahara Y, et al. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3. Nat Commun. 2016 Mar 24;7:10959.
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