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Accueil >> Signaling Pathways >> Cardiovascular

Cardiovascular

Cardiovascular

Cardiovascular

The cardiovascular system consists of the heart, blood and blood vessels. These organs form the 3 major closed circulation systems in the body, i.e., the pulmonary, coronary and systemic circulations. Cardiovascular disease includes heart disease, vascular diseases of the brain and kidney, and peripheral arterial diseases. Cardiovascular disease is the leading cause of death globally. Studies on cardiovascular regulation are important to provide a better understanding of this group of diseases and to help improve the corresponding treatment.

Targets for  Cardiovascular

Products for  Cardiovascular

  1. Cat.No. Nom du produit Informations
  2. GC47663 Methylene Blue (hydrate) L'hydrate de bleu de méthylène (Basic Blue 9) est un inhibiteur de la guanylyl cyclase (sGC), de la monoamine oxydase A (MAO-A) et de la NO synthase (NOS). Methylene Blue (hydrate) Chemical Structure
  3. GC46170 Methylspinazarin A bacterial metabolite and COMT inhibitor Methylspinazarin Chemical Structure
  4. GC49194 Metolazone-d7 An internal standard for the quantification of metolazone Metolazone-d7 Chemical Structure
  5. GC52250 Mevalonate (lithium salt) An intermediate in the mevalonate pathway Mevalonate (lithium salt) Chemical Structure
  6. GC47679 Minoxidil-d10 An internal standard for the quantification of minoxidil Minoxidil-d10 Chemical Structure
  7. GC44198 MitoA MitoA is a ratiometric mass spectrometry probe that can be used for assessing changes in H2S within mitochondria in vivo. MitoA Chemical Structure
  8. GC40624 MMP-3 Inhibitor VIII Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins to enable cell migration. MMP-3 Inhibitor VIII Chemical Structure
  9. GC18616 MMP-8 Inhibitor I MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM. MMP-8 Inhibitor I Chemical Structure
  10. GC48469 Moexipril-d5 An internal standard for the quantification of moexipril Moexipril-d5 Chemical Structure
  11. GC48538 MRS2179 (ammonium salt hydrate) A P2Y1 receptor antagonist MRS2179 (ammonium salt hydrate) Chemical Structure
  12. GC48399 MTP 131 (acetate) A mitochondria-targeted peptide antioxidant MTP 131 (acetate) Chemical Structure
  13. GC45515 MX1013 MX1013 est un puissant inhibiteur de caspase dipeptidique irréversible avec une activité anti-apoptotique. MX1013 inhibe la caspase3 humaine recombinante avec une IC50 de 30nM. MX1013 Chemical Structure
  14. GC47712 Mycophenolate Mofetil-d4 Le mycophénolate mofétil-d4 est le mycophénolate mofétil marqué au deutérium. Le mycophénolate mofétil (RS 61443) est le promédicament morpholinoéthylester de l'acide mycophénolique. Le mycophénolate mofétil inhibe la synthèse de novo des purines via l'inhibition de l'inosine monophosphate déshydrogénase (IMPDH). Le mycophénolate mofétil présente des effets antiprolifératifs lymphocytaires sélectifs impliquant À la fois les lymphocytes T et B, empêchant la formation d'anticorps. Mycophenolate Mofetil-d4 Chemical Structure
  15. GC44320 N-Arachidonoyl-L-Serine Arachidonoyl amides of both amino acids and neurotransmitters such as dopamine have been previously reported in the literature. N-Arachidonoyl-L-Serine Chemical Structure
  16. GC49399 N-Desbutyl Dronedarone (hydrochloride) Le chlorhydrate de débutyldronédarone (SR35021), principal métabolite de la dronédarone, est un inhibiteur sélectif du récepteur de l'hormone thyroÏdienne α1 (TRα1). N-Desbutyl Dronedarone (hydrochloride) Chemical Structure
  17. GC44345 N-Desethyl Vardenafil N-Desethyl vardenafil is a metabolite of vardenafil , a phosphodiesterase 5 inhibitor, that is formed by the action of cytochrome P450 (CYP)3A4 and CYP3A5. N-Desethyl Vardenafil Chemical Structure
  18. GC49683 N-desethyl-N-methyl Vardenafil A potential impurity found in commercial preparations of vardenafil N-desethyl-N-methyl Vardenafil Chemical Structure
  19. GC52045 N-desmethyl Azelastine La N-desméthyl azélastine est un métabolite actif principal de l'azélastine qui est métabolisé par voie oxydative par le système enzymatique du cytochrome P450 avec un taux de liaison aux protéines de 97 % et une demi-vie d'élimination de 54 heures. N-desmethyl Azelastine Chemical Structure
  20. GC52132 N-desmethyl Diltiazem (hydrochloride) N-desmethyl Diltiazem (hydrochloride) Chemical Structure
  21. GC47756 N-desmethyl Rosuvastatin (sodium salt hydrate) An active metabolite of rosuvastatin N-desmethyl Rosuvastatin (sodium salt hydrate) Chemical Structure
  22. GC44350 N-Desmethyl Sildenafil Le N-Desmethyl Sildenafil (Desmethylsildenafil) est un métabolite majeur du Sildenafil. N-Desmethyl Sildenafil Chemical Structure
  23. GC44351 N-Desmethyl Sildenafil (citrate) N-Desmethyl sildenafil is a major metabolite of sildenafil. N-Desmethyl Sildenafil (citrate) Chemical Structure
  24. GC41270 N-desmethyl Zolmitriptan N-desmethyl Zolmitriptan (DZT) is an active metabolite of the serotonin (5-HT) receptor subtype 5-HT1B and 5-HT1D agonist zolmitriptan. N-desmethyl Zolmitriptan Chemical Structure
  25. GC44396 N-Hippuryl-His-Leu (hydrate) N-Hippuryl-His-Leu (hydrate) is a synthetic substrate for angiotensin-converting enzyme (ACE) that has been used in the in vitro identification of ACE inhibitors., N-Hippuryl-His-Leu (hydrate) Chemical Structure
  26. GC52007 N-hydroxylamine Dapsone An active metabolite of dapsone N-hydroxylamine Dapsone Chemical Structure
  27. GC20172 N-Isopropylphthalimide N-Isopropylphthalimide Chemical Structure
  28. GC47784 N-methyl-2-HOBA (hydrochloride) A methylated form of 2-HOBA N-methyl-2-HOBA (hydrochloride) Chemical Structure
  29. GC52069 N-Methyl-4-pyridone-5-carboxamide A metabolite of nicotinic acid and a uremic toxin N-Methyl-4-pyridone-5-carboxamide Chemical Structure
  30. GC47806 N-p-Tosyl-Gly-Pro-Lys-pNA (acetate) A colorimetric plasmin substrate N-p-Tosyl-Gly-Pro-Lys-pNA (acetate) Chemical Structure
  31. GC49138 Naphazoline-d4 (hydrochloride) An internal standard for the quantification of naphazoline Naphazoline-d4 (hydrochloride) Chemical Structure
  32. GC49301 Nesiritide (acetate) A natriuretic peptide Nesiritide (acetate) Chemical Structure
  33. GC44376 Neuromedin N (trifluoroacetate salt) Neuromedin N is a neurotensin-like hexapeptide that is synthesized from the same precursor as neurotensin. Neuromedin N (trifluoroacetate salt) Chemical Structure
  34. GC49264 Neuromedin U-23 (rat) (trifluoroacetate salt) A peptide NMUR agonist Neuromedin U-23 (rat) (trifluoroacetate salt) Chemical Structure
  35. GC47768 Neuromedin U-25 (human) (trifluoroacetate salt) A neuropeptide with diverse roles Neuromedin U-25 (human) (trifluoroacetate salt) Chemical Structure
  36. GC44384 Neuropeptide Y (3-36) (human, rat) (trifluoroacetate salt) Neuropeptide Y (NPY) (3-36) is a C-terminal fragment of NPY, a neuropeptide involved in controlling appetite, blood pressure, cardiac contractility, and intestinal secretion. Neuropeptide Y (3-36) (human, rat) (trifluoroacetate salt) Chemical Structure
  37. GC52384 NFAT Inhibitor (cell-permeable) (trifluoroacetate salt) A cell-permeable form of NFAT inhibitor NFAT Inhibitor (cell-permeable) (trifluoroacetate salt) Chemical Structure
  38. GC48837 NG,NG-dimethyl-L-Arginine-d6 (hydrochloride) NG,NG-diméthyl-L-Arginine-d6 (chlorhydrate) est le dichlorhydrate de diméthylarginine asymétrique marqué au deutérium. NG,NG-dimethyl-L-Arginine-d6 (hydrochloride) Chemical Structure
  39. GC49511 Nicorandil N-oxide A metabolite of nicorandil Nicorandil N-oxide Chemical Structure
  40. GC49086 Nicorandil-d4 An internal standard for the quantification of nicorandil Nicorandil-d4 Chemical Structure
  41. GC49090 Nilvadipine-d4 An internal standard for the quantification of nilvadipine Nilvadipine-d4 Chemical Structure
  42. GC47775 Nimodipine-d7 An internal standard for the quantification of nimodipine Nimodipine-d7 Chemical Structure
  43. GC47776 Nisoldipine-d6 An internal standard for the quantification of nisoldipine Nisoldipine-d6 Chemical Structure
  44. GP10011 Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell Chemical Structure
  45. GC44446 NO-Losartan A Angiotensin II is a hormone that plays an important role in regulating blood pressure. NO-Losartan A Chemical Structure
  46. GC52019 Norpropranolol (hydrochloride) An active metabolite of propranolol Norpropranolol (hydrochloride) Chemical Structure
  47. GC48801 Nylidrin An agonist of β-ARs and antagonist of NR1A/2B subunit-containing NMDA receptors Nylidrin Chemical Structure
  48. GC49349 O-Desethyl Sildenafil A metabolite of sildenafil O-Desethyl Sildenafil Chemical Structure
  49. GC44492 O-Desmethyl Metoprolol O-Desmethyl metoprolol is the major active metabolite of the β1-adrenergic receptor blocker metoprolol. O-Desmethyl Metoprolol Chemical Structure
  50. GC49428 O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine A major metabolite of amlodipine O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine Chemical Structure
  51. GC47815 Octacosanoic Acid L'acide octacosanoÏque est un acide gras saturé À très longue chaÎne. Octacosanoic Acid Chemical Structure
  52. GC52318 Oleic Acid-13C5 An internal standard for the quantification of oleic acid Oleic Acid-13C5 Chemical Structure
  53. GC44497 Oleic Acid-2,6-diisopropylanilide AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol. Oleic Acid-2,6-diisopropylanilide Chemical Structure
  54. GC47819 Oleoyl Ethanolamide-d2 An internal standard for the quantification of oleoyl ethanolamide Oleoyl Ethanolamide-d2 Chemical Structure
  55. GC47824 Olmesartan Medoxomil-d6 L'olmésartan médoxomil-d6 (CS 866-d6) est l'olmésartan médoxomil marqué au deutérium. Olmesartan Medoxomil-d6 Chemical Structure
  56. GC49677 Olmesartan-d6 An internal standard for the quantification of olmesartan Olmesartan-d6 Chemical Structure
  57. GC44518 Osteocalcin (1-49) (human) (trifluoroacetate salt) Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. Osteocalcin (1-49) (human) (trifluoroacetate salt) Chemical Structure
  58. GC48847 Oxprenolol-d7 An internal standard for the quantification of oxprenolol Oxprenolol-d7 Chemical Structure
  59. GC18332 Oxyphenonium (bromide) Oxyphenonium is an antagonist of muscarinic acetylcholine receptors that binds to muscarinic receptors on isolated guinea pig atria and ileum (Kds = 0.11 and 0.17 nM, respectively). Oxyphenonium (bromide) Chemical Structure
  60. GC49414 p-Cresol Glucuronide A metabolite of p-cresol p-Cresol Glucuronide Chemical Structure
  61. GC52342 P4pal10 (trifluoroacetate salt) A PAR4 and FPR2 antagonist and an FFAR2 agonist P4pal10 (trifluoroacetate salt) Chemical Structure
  62. GC44531 PACAP (1-27) (human, mouse, ovine, porcine, rat) (trifluoroacetate salt) Pituitary adenylate cyclase-activating peptide (PACAP) (1-27) is a PACAP receptor agonist with IC50 values of 3, 2, and 5 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors expressed in CHO cells. PACAP (1-27) (human, mouse, ovine, porcine, rat) (trifluoroacetate salt) Chemical Structure
  63. GC44533 PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt) Pituitary adenylate cyclase-activating peptide (PACAP) (6-27) is a PACAP receptor antagonist with IC50 values of 1,500, 600, and 300 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors expressed in CHO cells. PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt) Chemical Structure
  64. GC47855 PAF C-16-d4 An internal standard for the quantification of PAF C16 PAF C-16-d4 Chemical Structure
  65. GC44541 PAF C-18 PAF C-18 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the "remodeling" and 'de novo' pathways. PAF C-18 Chemical Structure
  66. GC41450 PAF C-18:1 PAF C-18:1 is a naturally occurring phospholipid produced by cells upon stimulation and plays a role in the establishment and maintenance of the inflammatory response. PAF C-18:1 Chemical Structure
  67. GC41580 Palmitelaidic Acid methyl ester Palmitoleic acid is a common constituent of the triglycerides of human adipose tissue. Palmitelaidic Acid methyl ester Chemical Structure
  68. GC49024 Palmitic Acid MaxSpec® Standard A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Palmitic Acid MaxSpec® Standard Chemical Structure
  69. GC49023 Palmitic Acid-d9 MaxSpec® Standard A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Palmitic Acid-d9 MaxSpec® Standard Chemical Structure
  70. GC44544 Palmitoleic Acid (sodium salt) Palmitoleic acid is an ω-7 monounsaturated fatty acid that is a common constituent of the triglycerides of human adipose tissue. Palmitoleic Acid (sodium salt) Chemical Structure
  71. GC47867 Palmitoylcholine (chloride) An acyl choline Palmitoylcholine (chloride) Chemical Structure
  72. GP10009 Papilostatin-2 Papilostatin-2 Papilostatin-2 Chemical Structure
  73. GC44557 PAR2 (1-6) (mouse, rat) PAR2 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse and rat PAR2. PAR2 (1-6) (mouse, rat) Chemical Structure
  74. GC44566 Parathyroid Hormone (1-13) (trifluoroacetate salt) Parathyroid hormone (PTH) (1-13) is an N-terminal fragment of PTH (1-34). Parathyroid Hormone (1-13) (trifluoroacetate salt) Chemical Structure
  75. GC44573 PAz-PC Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. PAz-PC Chemical Structure
  76. GC44590 Pellitorine La pellitorine est un composé isolé des racines de Piper nigrum. La pellitorine présente de fortes activités cytotoxiques contre les lignées cellulaires HL60 et MCT-7. Pellitorine a le potentiel pour la recherche de maladies cancéreuses. Pellitorine Chemical Structure
  77. GC48829 Pentoxifylline-d6 An internal standard for the quantification of pentoxifylline Pentoxifylline-d6 Chemical Structure
  78. GC44599 Perindoprilat Le périndoprilate (S 9780) est un inhibiteur de l'enzyme de conversion de l'angiotensine (ECA) avec une valeur IC50 allant de 1,5 À 3,2 nM. Perindoprilat Chemical Structure
  79. GC52177 Perphenazine Sulfoxide Perphenazine Sulfoxide Chemical Structure
  80. GC44616 PGPC

    PGPC is an oxidized phospholipid that can be formed under conditions of oxidative stress.

     PGPC Chemical Structure
  81. GC46202 Phenoxybenzamine-d5 (hydrochloride) La phénoxybenzamine-d5 (chlorhydrate) est le chlorhydrate de phénoxybenzamine marqué au deutérium. Phenoxybenzamine-d5 (hydrochloride) Chemical Structure
  82. GC45999 Phentolamine-d4 (hydrochloride) An internal standard for the quantification of phentolamine Phentolamine-d4 (hydrochloride) Chemical Structure
  83. GC44627 Phenylephrine Glucuronide Phenylephrine glucuronide is a metabolite of the α1A-adrenergic receptor agonist phenylephrine . Phenylephrine Glucuronide Chemical Structure
  84. GC44628 Phenylephrine-3-O-Sulfate Phenylephrine-3-O-sulfate is metabolite of the α1A-adrenergic receptor agonist phenylephrine formed via sulfation. Phenylephrine-3-O-Sulfate Chemical Structure
  85. GC44633 Phosphatidylserines (bovine) Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. Phosphatidylserines (bovine) Chemical Structure
  86. GC18522 Phosphatidylserines (sodium salt) Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. Phosphatidylserines (sodium salt) Chemical Structure
  87. GC18323 Picotamide Le picotamide est un inhibiteur combiné de la synthase et du récepteur de la thromboxane A2 (TxA2). Picotamide Chemical Structure
  88. GC49193 Pilsicainide (hydrochloride) Le pilsicaïnide (chlorhydrate) (SUN-1165) est un inhibiteur des canaux sodiques actif par voie orale et un puissant agent antiarythmique de classe Ic. Pilsicainide (hydrochloride) Chemical Structure
  89. GC18707 Pimprinine Pimprinine is an alkaloid originally isolated from Streptomyces that has diverse biological activities, including anticonvulsant, antiplatelet, and antimicrobial properties. Pimprinine Chemical Structure
  90. GC41174 Pinane Thromboxane A2 Pinane thromboxane A2 (PTA2) is a stable analog of TXA2. Pinane Thromboxane A2 Chemical Structure
  91. GC47960 Pirmenol A class I antiarrhythmic agent Pirmenol Chemical Structure
  92. GC49340 Pitavastatin lactone-d4 An internal standard for the quantification of pitavastatin lactone Pitavastatin lactone-d4 Chemical Structure
  93. GC44659 PKSI-527 PKSI-527 is an inhibitor of plasma kallikrein (Ki = 0.81 μM). PKSI-527 Chemical Structure
  94. GP10089 Platelet Membrane Glycoprotein IIB Peptide (296-306)

    Inhibits platelet aggregation

     Platelet Membrane Glycoprotein IIB Peptide (296-306) Chemical Structure
  95. GC44669 POV-PC Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. POV-PC Chemical Structure
  96. GC47966 PPACK (trifluoroacetate salt) An antithrombin peptide PPACK (trifluoroacetate salt) Chemical Structure
  97. GC47967 Prasugrel-d5 Le prasugrel-d5 est du prasugrel marqué au deutérium. Prasugrel-d5 Chemical Structure
  98. GC40220 Pravastatin-d3 (sodium salt) Le sel de sodium de pravastatine-d3 (CS-514-d3) est le sel de sodium de pravastatine marqué au deutérium. Pravastatin-d3 (sodium salt) Chemical Structure
  99. GC18686 Prazobind Prazobind (SZL 49), un analogue de la prazosine, est un puissant bloqueur des récepteurs alpha 1-adrénergiques. Prazobind Chemical Structure
  100. GC45891 Prazosin-d8 An internal standard for the quantification of prazosin Prazosin-d8 Chemical Structure
  101. GP10072 Pro-Adrenomedullin (153-185), human

    Vasodilator

     Pro-Adrenomedullin (153-185), human Chemical Structure

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