Cardiovascular
Cardiovascular
The cardiovascular system consists of the heart, blood and blood vessels. These organs form the 3 major closed circulation systems in the body, i.e., the pulmonary, coronary and systemic circulations. Cardiovascular disease includes heart disease, vascular diseases of the brain and kidney, and peripheral arterial diseases. Cardiovascular disease is the leading cause of death globally. Studies on cardiovascular regulation are important to provide a better understanding of this group of diseases and to help improve the corresponding treatment.
Targets for Cardiovascular
Products for Cardiovascular
- Cat.No. Nom du produit Informations
- GC52035 Esmolol Acid (hydrochloride) An active metabolite of esmolol
- GC47307 Esmolol-d7 (hydrochloride) An internal standard for the quantification of esmolol
- GC33760 ETC-1002 (ESP-55016) ETC-1002 (ESP-55016) (ETC-1002) est un inhibiteur de l'ATP-citrate lyase (ACL).
- GC52303 Ethyl Mycophenolate A potential impurity found in commercial preparations of mycophenolate mofetil
- GC48916 Etilefrine (hydrochloride) A sympathomimetic amine
- GC49762 Etiocholanedione A neurosteroid
- GC32451 Examorelin (Hexarelin) A peptide agonist of GHS-R
- GC43646 Ezetimibe Hydroxy Glucuronide Ezetimibe hydroxy glucuronide is a minor phase II glucuronide metabolite of ezetimibe .
- GC49230 Ferroprotoporphyrin La ferroprotoporphyrine, un complexe de fer ferreux et d'une porphyrine, est un inhibiteur isostérique de la liaison des acides gras À la protéine de liaison des acides gras du foie de rat.
- GC49518 Fluindione A vitamin K antagonist
- GC45761 Flupirtine-d4 (hydrochloride) Le chlorhydrate de flupirtine-d4 (D 9998-d4) est la flupirtine marquée au deutérium.
- GC47367 Fluvastatin (sodium salt hydrate) An HMG-CoA reductase inhibitor
- GC47371 Fosinopril-d7 (sodium salt) An internal standard for the quantification of fosinopril
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GC49089
FR900359
A cyclic depsipeptide and an inhibitor of Gαq, Gα11, and Gα14
-
GC18260
FTase Inhibitor I
L'inhibiteur de FTase I est un inhibiteur puissant de la farnésyltransférase (FTase ; IC50 = 21 nM) qui est plus de 30 fois sélectif pour la FTase par rapport à la géranylgeranyl transférase (GGTase ; IC50 = 790 nM).
- GC47385 Furosemide-d5 An internal standard for the quantification of furosemide
- GC47387 G6PDi-1 Le G6PDi-1 est un inhibiteur réversible et non compétitif de la glucose-6-phosphate déshydrogénase (G6PD) avec une IC50 de 0,07μM.
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GC43727
Ganglioside GD1a mixture (sodium salt)
Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver.
- GC43732 Ganglioside GM3 Mixture (sodium salt) Ganglioside GM3 is a monosialoganglioside that demonstrates antiproliferative and proapoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation.
- GC49303 Ganoderic Acid DM L'acide ganodérique DM, un triterpénoÏde naturel isolé de Ganoderma lucidum, induit des dommages À l'ADN, l'arrêt du cycle cellulaire G1 et l'apoptose dans les cellules cancéreuses du sein humain.
- GP10107 Gap 26
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GP10119
Gap 27
A connexin-mimetic peptide
- GC49416 Gap 27 (trifluoroacetate salt) A connexin-mimetic peptide
- GC47397 Gemfibrozil-d6 An internal standard for the quantification of gemfibrozil
-
GC43745
Geranyl Pyrophosphate (triammonium salt)
Le pyrophosphate de géranyle (sel de triammonium) est un intermédiaire clé dans la voie de biosynthèse des isoprénoïdes (IBP).
- GC48744 Gliclazide-d4 An internal standard for the quantification of gliclazide
- GC47413 Glycoursodeoxycholic Acid-d4 A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications
- GC49509 Glycyl-L-Glutamine (hydrate) A dipeptide fragment of β-endorphin
- GC18788 Graphislactone A Graphislactone A is an antioxidant produced by Cephalosporium IFB-E001 and M.
- GP10115 GTP-Binding Protein Fragment, G alpha
- GC49117 Guanadrel Le guanadrel est un inhibiteur adrénergique postganglionnaire actif par voie orale du spirocétal.
- GC47416 Guanfacine-13C,15N3 An internal standard for the quantification of guanfacine
- GC45678 Guanoclor Guanoclor (Vatensol) est un inhibiteur de la dopamine bêta-hydroxylase (DBH) qui interfère avec la synthèse de la noradrénaline.
- GC43800 GW 9578 GW9578 est un agoniste PPARα sélectif de sous-type (EC50 de 5 et 50 nM pour PPAR-α murin et humain) avec une puissante activité hypolipémiante.
- GC49255 GYKI 52466 (hydrochloride) An allosteric AMPA receptor antagonist
- GC47418 Gymnoascolide A A fungal metabolite with fungicidal and vasodilatory activities
- GC49305 H-Arg-Gly-Asp-Cys-OH (trifluoroacetate salt) An RGD-containing tetrapeptide
- GC43802 HA-1004 (hydrochloride) HA-1004 is an inhibitor of protein kinase G (PKG) and PKA (Kis = 1.4 and 2.3 μM, respectively).
- GC43803 HA-1077 (hydrochloride) Fasudil (HA-1077; AT877) Le dihydrochlorydle est un inhibiteur RHOA / ROCK non spécifique et a également un effet inhibiteur sur les protéines kinases, avec un KI de 0,33 μ M pour ROCK1, IC50S de 0,158 offlineefficient_models_2022q2.md;M, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively.en_fr_2022q1.mdHA-1077 (hydrochloride) is also a potent Ca2+ channel antagonist and vasodilator.en_fr_2022q1.md
- GC49882 Hemokinin 1 (human) (trifluoroacetate salt) A peptide agonist of NK1 receptors
-
GP10040
heparin cofactor II precursor (SERPIND1) fragment [Homo sapiens]
Thrombin inhibitor
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GP10027
heparin cofactor II precursor fragment [Homo sapiens]
Thrombin inhibitor
- GC49543 Hepcidin-25 (trifluoroacetate salt) A peptide hormone
- GC47423 Heptaminol An aliphatic amine with cardiotonic and sympathomimetic activities
- GC45469 Hexacosanoic Acid-d4
- GC49091 Hirudin (54-65; non-sulfated) (trifluoroacetate salt) A desulfated peptide fragment of hirudin
- GC48897 Homocarnosine L'homocarnosine est un dipeptide d'acide γ-aminobutyrique (GABA) et d'histidine unique au cerveau.
- GC49496 Homocitrulline-d3 An internal standard for the quantification of homocitrulline
- GC43869 Homovanillic Acid sulfate (sodium salt) Homovanillic acid sulfate is a phenol found in olive oil and a dopamine metabolite.
- GC47440 Hydrocortisone-d4 An internal standard for the quantification of hydrocortisone
- GC47441 Hydroflumethiazide-13C-d2 An internal standard for the quantification of hydroflumethiazide
- GC49250 Hydroxydehydro Nifedipine Carboxylate A metabolite of nifedipine
- GC43883 Hymeglusin L'hyméglusine, en tant qu'antibiotique fongique β-lactone, est un inhibiteur de la HMG-CoA synthase (IC50 = 0,12 μM).
- GC17816 I-BOP TP specific agonist
- GC43910 I-SAP I-SAP is a high affinity TP receptor antagonist.
- GC43890 ICI 216140 Bombesin is a peptide, originally isolated from the skin of the European fire-bellied toad, with pressor and sympathoexcitatory activity.
- GC40485 Icosabutate L'icosabutate, un acide gras polyinsaturé ω-3 actif par voie orale, est un dérivé de l'acide eicosapentaénoÏque (EPA).
- GC49195 Indapamide-13C-d3 An internal standard for the quantification of indapamide
- GC48621 INNO-8875 INNO-8875 (INO-8875), un mimétique de l'adénosine, est un agoniste hautement sélectif des récepteurs de l'adénosine A1.
- GC45728 Iohexol-d5 Iohexol-d5 est Iohexol marqué au deutérium. Iohexol est un agent de contraste radiographique et peut être appliqué pour la myélographie, la tomographie informatisée(cisternographie, ventriculographie) et l'imagerie MicroCT in vivo.
- GC49493 IRL 1620 (trifluoroacetate salt) A peptide ETB receptor agonist
- GC49634 Isoflupredone L'isofluprédone appartient À la classe des corticostéroÏdes et exerce son effet en se liant aux récepteurs glucocorticoÏdes et minéralocorticoÏdes des animaux, tels que les chevaux.
- GC49343 Isoproterenol-d7 (hydrochloride) An internal standard for the quantification of isoproterenol
- GC47479 JP-1302 (hydrochloride hydrate) An α2C-adrenergic receptor antagonist
- GC48432 KB-130015 KB-130015 (KB015) est un inhibiteur ThRα et ThRβ (Thyroid Hormone Receptor) actif et puissant par voie orale, avec des valeurs IC50 de 4,5 et 5,1 μM, respectivement.
- GC43997 KDdiA-PC KDdiA-PC est une sorte de LDL oxydée (oxLDL) et est un ligand pour le récepteur CD36 des macrophages.
- GC44011 KOdiA-PC Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic.
- GC44013 KR-32568 KR-32568 is an inhibitor of the sodium-hydrogen exchanger isoform-1 (NHE-1; IC50 = 230 nM).
- GC47532 KUS121 A VCP modulator
- GC49436 L-3-n-Butylphthalide A phthalide with antiplatelet and neuroprotective activities
- GC52310 L-Arginine-13C6 (hydrochloride) An internal standard for the quantification of L-arginine
- GC49374 L-Arginine-d7 (hydrochloride) Le chlorhydrate de L-Arginine-d7 ((S)-(+)-Arginine-d7) est le chlorhydrate de L-Arginine marqué au deutérium.
- GC47563 L-Glutamic Acid (ammonium salt) An excitatory neurotransmitter
- GC49377 L-Glutamine-d5 An internal standard for the quantification of L-glutamine
- GC44062 L-hydroxy Arginine (acetate) L-hydroxy Arginine is a substrate for nitric oxide synthase in the catabolism of L-arginine to form nitric oxide.
- GC48937 L-Tyrosine-13C9,15N An internal standard for the quantification of L-tyrosine
- GC52497 Lactosylceramide (porcine RBC) A sphingolipid
- GC40142 Lactosylceramides (bovine buttermilk) Lactosylceramide (LacCer) is an endogenous bioactive sphingolipid.
- GC40807 Levonordefrin La lévonordefrine, une alternative courante À la lévoépinéphrine comme vasoconstricteur dans les préparations anesthésiques locales dentaires, est généralement utilisée À des concentrations cinq fois plus élevées.
- GC40239 Limaprost-d3 Limaprost-d3 is intended for use as an internal standard for the quantification of limaprost by GC- or LC-MS.
- GC49738 Lipid 29 An ionizable amino lipid
- GC45501 Lisinopril-d5
- GC52281 Losartan Azide A potential impurity in commercial preparations of losartan
- GC44093 Lutein Lutein is a natural yellow carotenoid, which can be found in plants, egg yolks, and in the human retina.
- GC41452 Luteoloside Luteoloside is a flavonoid that has been found in many Chinese herbs with diverse biological activities.
- GC49916 Lys-(Des-Arg9, Leu8)-Bradykinin (trifluoroacetate salt) A bradykinin B1 receptor antagonist
- GC47587 Lyso-PAF C-16-d4 An internal standard for the quantification of LysoPAF C16
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GC18241
Lysophosphatidylcholines
Lysophosphatidylcholines are produced by hydrolysis of the fatty acid of phosphatidylcholine at either the sn-1 or sn-2 position by phospholipase A2 (PLA2) or by lecithin-cholesterol acyltranferase (LCAT), which transfers the fatty acid to cholesterol.
- GC44112 Mabuterol Mabuterol is an agonist of the β2-adrenergic receptor (β2-AR).
- GC47597 Manidipine-d4 An internal standard for the quantification of manidipine
- GC41595 Matairesinol Matairesinol confère des effets anti-allergiques dans un modèle murin de dermatite allergique.
- GC49486 Meglutol-d3 An internal standard for the quantification of meglutol
- GC45508 MEGX (hydrochloride)
- GC40078 Memantine-d6 (hydrochloride) Memantine-d6 is intended for use as an internal standard for the quantification of memantine by GC- or LC-MS.
-
GC44155
Menaquinone 9
La ménakinone 9 (MK-9) est un analogue de la vitamine K2 qui a été trouvé dans diverses bactéries, y compris E.
- GC44170 Metaraminol (tartrate) Metaraminol is a vasoconstrictor.
- GC47645 Methidathion An organophosphate insecticide
- GC48661 Methylatropine (nitrate) A muscarinic acetylcholine receptor antagonist
- GC44180 Methylcarbamyl PAF C-16 Methylcarbamyl PAF C-16 is a stable analog of PAF C-16 with a half-life greater than 100 minutes in platelet poor plasma due to its resistance to degradation by PAF-AH.
- GC41639 Methyldopate Le méthyldopate est un promédicament d'ester éthylique de l'α-méthyldopa