(S)-IDO1-IN-5 |
| Catalog No.GC38878 |
(S)-IDO1-IN-5 (Exemple 1B) est un isomère S actif de IDO1-IN-5. (S)-IDO1-IN-5 se lie À IDOL avec une valeur IC50 inférieure À 1,5 μμ. IDO1-IN-5 est un inhibiteur puissant, sélectif et pénétrant dans le cerveau de l'activité de l'indoleamine 2,3-dioxygénase 1 (IDO1), se lie À l'apo-IDO1 dépourvu d'hème plutÔt qu'À l'IDO1 lié À l'hème mature.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2166616-76-6
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
(S)-IDO1-IN-5 is the S-isomer of IDO1-IN-5. IDO1-IN-5 is a potent, selective and brain penetrated inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[1].
[1]. Frank C. Dorsey, et al. Abstract 5245: Identification and characterization of the IDO1 inhibitor LY3381916. Cancer Research. 2018, 78(13).
Average Rating: 5 (Based on Reviews and 17 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *