SAHM1 |
| Catalog No.GC50470 |
SAHM1, un peptide mimétique d'une forme négative dominante de type cerveau (MAML), inhibe la formation du complexe de transcription canonique Notch.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2050906-89-1
Sample solution is provided at 25 µL, 10mM.
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Notch pathway inhibitor - stabilized hydrocarbon-stapled alpha helical peptide. Targets the protein-protein interface and prevents Notch complex assembly.
Ashley et al (2015) Notch signaling promotes osteoclast maturation and resorptive activity. J Cell Biochem 116 2598 PMID:25914241 |Bagheri et al (2018) Notch pathway is active during osteogenic differentiation of human bone marrow mesenchymal stem cells induced by pulsed electromagnetic fields. J.Tissue Eng.Regen.Med. 12 304 PMID:28482141 |KleinJan et al (2018) The Notch pathway inhibitor stapled a-helical peptide derived from mastermind-like 1 (SAHM1) abrogates the hallmarks of allergic asthma. J.Allergy Clin.Immunol. 142 76 PMID:29111218
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