Telratolimod (MEDI 9197) (Synonyms: MEDI9197, 3M-052) |
| Catalog No.GC33076 |
Telratolimod (MEDI 9197) (MEDI9197) est un puissant agoniste des récepteurs de type toll 7/8 (TLR7/8), avec une activité antitumorale.
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Cas No.: 1359993-59-1
Sample solution is provided at 25 µL, 10mM.
Telratolimod is a toll like receptors 7/8 (TLR7/8) agonist, with antitumor activity.
Telratolimod (3M-052) is a toll like receptors 7/8 (TLR7/8) agonist, with antitumor activity[1].
Telratolimod (50 μg) inhibits the tumor volume, and more potently blocks tumor gowth in combination with CpG ODN in BALB/c mice bearing CT26 colon carcinoma cells. Telratolimod (100 μg) plus 200 μg of CpG ODN slows tumor growth and prolongs survival of mice bearing large tumors[1].
[1]. Zhao BG, et al. Combination therapy targeting toll like receptors 7, 8 and 9 eliminates large established tumors. J Immunother Cancer. 2014 May 13;2:12.
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