Thalidomide-5-OH |
| Catalog No.GC60361 |
La thalidomide-5-OH est le ligand céréblon À base de thalidomide utilisé dans le recrutement de la protéine CRBN. La thalidomide-5-OH peut être connectée au ligand de la protéine par un lieur pour former des PROTAC.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 64567-60-8
Sample solution is provided at 25 µL, 10mM.
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Thalidomide-5-OH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-OH can be connected to the ligand for protein by a linker to form PROTACs[1].
[1]. Megan G Marks, et al. Effects of Putative Hydroxylated Thalidomide Metabolites on Blood Vessel Density in the Chorioallantoic Membrane (CAM) Assay and on Tumor and Endothelial Cell Proliferation. Biol Pharm Bull. 2002 May;25(5):597-604.
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