>>Signaling Pathways>> PROTAC>> Ligand for E3 Ligase>>Thalidomide-5-OH

Thalidomide-5-OH

Catalog No.GC60361

탈리도마이드-5-OH는 CRBN 단백질 모집에 사용되는 탈리도마이드 기반 세레블론 리간드입니다. 탈리도마이드-5-OH는 링커에 의해 단백질에 대한 리간드에 연결되어 PROTAC를 형성할 수 있습니다.

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Thalidomide-5-OH Chemical Structure

Cas No.: 64567-60-8

Size 가격 재고 수량
100mg
US$46.00
재고 있음
250mg
US$74.00
재고 있음
500mg
US$111.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Thalidomide-5-OH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-OH can be connected to the ligand for protein by a linker to form PROTACs[1].

[1]. Megan G Marks, et al. Effects of Putative Hydroxylated Thalidomide Metabolites on Blood Vessel Density in the Chorioallantoic Membrane (CAM) Assay and on Tumor and Endothelial Cell Proliferation. Biol Pharm Bull. 2002 May;25(5):597-604.

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Average Rating: 5 ★★★★★ (Based on Reviews and 9 reference(s) in Google Scholar.)

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