Tie2 Inhibitor 7 |
| Catalog No.GC45054 |
Tie2 Inhibitor 7 blocks Tie2 kinase activity with a Ki value of 1.3 μM..
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1020412-97-8
Sample solution is provided at 25 µL, 10mM.
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Tie2 Inhibitor 7 blocks Tie2 kinase activity with a Ki value of 1.3 µM.. It has been shown to inhibit angiopoietin 1-induced Tie2 autophosphorylation and downstream signaling with an IC50 value of 0.3 µM. This compound can prevent endothelial cell tube formation and aberrant vessel growth in a rat model of Matrigel-induced choroidal neovascularization.
Average Rating: 5 (Based on Reviews and 9 reference(s) in Google Scholar.)
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