WRG-28 |
| Catalog No.GC38206 |
Le WRG-28 est un inhibiteur allostérique DDR2 sélectif À action extracellulaire, avec une IC50 de 230 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1913291-02-7
Sample solution is provided at 25 µL, 10mM.
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WRG-28 is a selective, extracellularly acting DDR2 allosteric inhibitor with an IC50 of 230 nM. WRG-28 uniquely inhibits receptor-ligand interactions via allosteric modulation of the receptor. WRG-28 inhibits tumor invasion and migration, as well as tumor-supporting roles of the stroma, and inhibits metastatic breast tumor cell colonization in the lungs by targeting DDR2[1].
[1]. Grither WR, et al. Inhibition of tumor-microenvironment interaction and tumor invasion by small-molecule allosteric inhibitor of DDR2 extracellular domain. Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7786-E7794.
Average Rating: 5 (Based on Reviews and 3 reference(s) in Google Scholar.)
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