YIL 781 hydrochloride |
| Catalog No.GC50049 |
Le chlorhydrate de YIL 781 est un antagoniste puissant et actif par voie orale des récepteurs de la ghréline (GHSR).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1640226-17-0
Sample solution is provided at 25 µL, 10mM.
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Ghrelin receptor antagonist (GHS-R1a) (Ki = 17 nM). Displays no significant affinity for the motilin receptor (Ki = 6 μM). Blocks the effects of ghrelin on insulin secretion both in vivo and in vitro. Improves glucose homeostasis in vivo.
Esler et al (2007) Small-molecule ghrelin receptor antagonists improve glucose tolerance, suppress appetite, and promote weight loss. Endocrinology 148 5175 PMID:17656463 |Moran and Dailey (2009) Gut peptides: targets for antiobesity drug development• Endocrinology 150 2526 PMID:19372201
Average Rating: 5 (Based on Reviews and 29 reference(s) in Google Scholar.)
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