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(+)-δ-Cadinene

カタログ番号GC49268

抗微生物および抗がん活性を持つセスキテルペン

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(+)-δ-Cadinene 化学構造

Cas No.: 483-76-1

サイズ 価格 在庫数 個数
50 mg
$60.00
在庫あり
100 mg
$114.00
在庫あり

Tel:(909) 407-4943 Email: sales@glpbio.com

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

(+)-Δ-Cadineneは、アップランドコットン(G. hirsutum)に見出され、抗菌、殺虫および抗がん活性を持つセスキテルペンである。S. pneumoniaeに対して有効であり(MIC = 31.25μg/ml)、A. stephensi、A. aegyptiおよびC. quinquefasciatusの第3幼虫に死亡率を引き起こす(それぞれLC50s = 8.23, 9.03,および9.86μg/ml)。(+)-Δ-Cadinene(10、50、および100μM)はOVCAR-3人間卵巣癌細胞のアポトーシスを誘導し増殖を阻害する。1,2,3,

1. Davis, G.D.、Essenberg, M. (+)-δ-Cadineneは綿花のセスキテルペンシクラーゼ活性の生成物である。Phytochemistry 39(3)553-567(1995) 2. PÉrez-LÓpez、Cirio、A.T.、Rivas-Galindo、V.M.ら。Schinus molle果実から分離された精油とδ-cadineneのStreptococcus pneumoniaeに対する活性。J.Essent.Oil Res.23(5)25-28(2011) 3.Govindarajan,M.,Rajeswary,M.,Benelli,G.Kadsura heteroclitaエッセンシャルオイル中のδ-cadinene、calareneおよびδ-4-careneはマラリア?デング熱およびフィラリア蚊に対する新規な幼虫殺虫剤である。Comb.Chem.High Throughput Screen19(7)565-571(2016) 4.Hui,L.-M.,Zhao,G.-D.,Zhao,J.-J.& # 948; -Cadineneはカスパーゼ依存性アポトーシスと細胞周期停止を介して卵巣癌細胞の増殖を抑制する。Int.J.Clin.Exp.Pathol8(6)6046-6056(2015)

Chemical Properties

Cas No. 483-76-1 SDF
Canonical SMILES CC([C@H]1[C@@]2([H])C(CCC(C)=C2)=C(CC1)C)C
Formula C15H24 M.Wt 204.4
溶解度 DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 1 mg/ml Storage -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.
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計算

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

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Average Rating: 5 ★★★★★ (Based on Reviews and 28 reference(s) in Google Scholar.)

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