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DBHDA

カタログ番号GC50369 Copy One-Click Copy Product Info

合成生物学用試薬;システインをデヒドロアラニンに変換する

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DBHDA 化学構造

Cas No.: 99584-96-0

サイズ 価格 在庫数 個数
50 mg
$110.00
在庫あり

Tel:(909) 407-4943 Email: sales@glpbio.com


顧客レビュー

カスタマーレビューに基づきます。

Sample solution is provided at 25 µL, 10mM.



Description of DBHDA

Reagent for synthetic biology; converts cysteine to dehydroalanine (Dha).

Chalker et al (2011) Methods for converting cysteine to dehydroalanine on peptides and proteins. Chem. Sci. 2 1666 |Wright et al (2016) Posttranslational mutagenesis: a chemical strategy for exploring protein side-chain diversity. Science 354 1465 PMID:27708059 |Mulder et al (2016) A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes. Nat.Chem.Biol. 12 523 PMID:27182664 |Lercher et al (2015) Generation of a synthetic GlcNAcylated nucleosome reveals regulation of stability by H2A-Thr101 GlcNAcylation. Nat.Commun. 25 7978 PMID:26305776

Chemical Properties of DBHDA

Cas No. 99584-96-0 SDF
Canonical SMILES NC(C(CCC(C(N)=O)Br)Br)=O
Formula C6H10Br2N2O2 M.Wt 301.96
溶解度 Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of DBHDA

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.3117 mL 16.5585 mL 33.117 mL
5 mM 662.3 μL 3.3117 mL 6.6234 mL
10 mM 331.2 μL 1.6558 mL 3.3117 mL
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**ストックソリューションを準備する際には、常にバイアルラベルおよび MSDS/CoA(オンラインで利用可能)で掲載された製品のロット固有分子量を使用してください。

計算

In vivo Formulation Calculator (Clear solution) of DBHDA

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for DBHDA

Average Rating: 5 ★★★★★ (Based on Reviews and 1 reference(s) in Google Scholar.)

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