Dihydronovobiocin |
| カタログ番号GC47228 |
クマリン系抗生物質
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 29826-16-2
Sample solution is provided at 25 µL, 10mM.
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Dihydronovobiocin is a coumarin antibiotic and derivative of novobiocin .1 It is active against the bacteria S. aureus, S. haemolyticus, D. pneumoniae, S. typhosa, K. pneumoniae, and P. multocida (MICs = 0.6, 2, 0.6, 10, 10, and 3 µg/ml, respectively).2 Dihydronovobiocin inhibits DNA gyrase subunit B with an IC50 value of 64.5 nM.3
1.Berger, J., and Batcho, A.D.Coumarin - glycoside antibioticsJ. Chromatogr. Lib.15101-158(1978) 2.Hoeksema, H.Dihydronovobiocin and derivatives thereof3,175,9441-9(1965) 3.Gevi, M., and Domenici, E.A scintillation proximity assay amenable for screening and characterization of DNA gyrase B subunit inhibitorsAnal. Biochem.300(1)34-39(2002)
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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