Fmoc-Gly-Gly-D-Phe-OtBu |
| カタログ番号GC38913 |
Fmoc-Gly-Gly-D-Phe-OtBu は、抗体薬物複合体 (ADC) の合成に使用される切断可能な ADC リンカーです。 Fmoc-Gly-Gly-D-Phe-OtBu は、Fmoc-Gly-Gly-Phe-OtBu の R 異性体です。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Fmoc-Gly-Gly-D-Phe-OtBu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Gly-Gly-D-Phe-OtBu is the R-isomer of Fmoc-Gly-Gly-Phe-OtBu [1].
[1]. Bak A, et al. Synthesis and evaluation of the physicochemical properties of esterase-sensitive cyclic prodrugs of opioid peptides using an (acyloxy)alkoxy linker. J Pept Res. 1999 Apr;53(4):393-402.
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