Alarin (human) |
カタログ番号GA20697
One-Click Copy Product Info
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Alarin（アラリン）は、Galanin-likeペプチド（GALP）RNAのスプライスバリアントから派生したものであり、APAHRSSTFPKWVTKTERGRQPLRSという配列を持っています。ガラニンペプチドファミリーの他のメンバーと同様に、皮膚微小血管で強力かつ用量依存的な血管収縮作用および抗浮腫活性を示します。 AlarinはGALP特異的受容体を活性化することができる可能性が低いため、GALPとわずか5つのアミノ酸しか共有していません。この神経ペプチドは、人間の神経芽細胞腫の節後細胞で発現することが報告されており、潜在的な腫瘍マーカーを表す可能性があります。 glpbioは、「特許侵害に対する免責事項または例外」を提供する法令または法律範囲内で本製品を提供しています（「免除使用」と呼ばれます）。これには米国35 U.S.C. § 271(e)(1)や欧州地域内ではBolar型例外規定などが含まれます。本製品の購入者または使用者は、免除使用に限定して使用し、すべての知的財産法および/または規制を遵守することに同意します。本製品の購入者は、商業契約（供給契約）の履行および知的財産権侵害の可能性に関連するすべてのクレームからglpbioを免責することに同意します。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 909409-86-5
Sample solution is provided at 25 µL, 10mM.
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Alarin, APAHRSSTFPKWVTKTERGRQPLRS, is derived from a splice variant of galanin-like peptide (GALP) RNA. It shows potent and dose-dependent vasoconstrictor and anti-edema activity in the cutaneous microvasculature, as was also observed with other member
| Cas No. | 909409-86-5 | SDF | |
| Formula | C127H205N43O35 | M.Wt | 2894.29 |
| 溶解度 | Soluble in DMSO | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
||
| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 345.5 μL | 1.7275 mL | 3.4551 mL |
| 5 mM | 69.1 μL | 345.5 μL | 691 μL |
| 10 mM | 34.6 μL | 172.8 μL | 345.5 μL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 27 reference(s) in Google Scholar.)