Prepro-Atrial Natriuretic Factor (26-55) (human) |
カタログ番号GA23378
One-Click Copy Product Info
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プレプロ-心房性ナトリウム利尿因子（26-55）（ヒト）（NT-pro-ANP（1-30））は、心房性ナトリウム利尿前駆体から派生する4つのペプチドホルモンのうちの1つです。また、長時間作用型ナトリウム利尿ペプチドとしても知られています。このペプチドには、心房性ナトリウム利尿因子と同等の強力な血管拡張作用があります。血管拡張は、粒状グアニル酸シクラーゼ活性化によるサイクリックGMPレベルの4〜5倍増加と関連しています。 プレプロ-心房性ナトリウム利尿因子（56-92）およびカリウレチックペプチドと同様に、充血性心不全を有する個人では高濃度で存在します。 これら3つのペプチド中で最大の前立腺素E2（PGE2）レベル上昇を引き起こします。 慢性的な心不全時に知られているPGE2の増加は、これらのペプチドに部分的に由来する可能性があります。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 112160-82-4
Sample solution is provided at 25 µL, 10mM.
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Prepro-atrial natriuretic factor (26-55) (human) (NT-pro-ANP (1-30)) is one of four peptide hormones derived from the atrial natriuretic prohormone. It is also known as long acting natriuretic peptide. The peptide has potent vasodilatory properties equ
| Cas No. | 112160-82-4 | SDF | |
| Formula | C152H236N38O51S3 | M.Wt | 3507.97 |
| 溶解度 | Soluble in DMSO | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 285.1 μL | 1.4253 mL | 2.8507 mL |
| 5 mM | 57 μL | 285.1 μL | 570.1 μL |
| 10 mM | 28.5 μL | 142.5 μL | 285.1 μL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)