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Fuberidazole

カタログ番号GD12835 Copy One-Click Copy Product Info

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Fuberidazole 化学構造

Cas No.: 3878-19-1

サイズ 価格 在庫数 個数
250mg
$133.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.



Description of Fuberidazole

Fuberidazole (BAY 33172; Furidazole) is a fungicide. Fuberidazole shows a synergistic effect with cucurbituril (CB) macromolecules, such as CB7 and CB8. Studies have shown that, CB8 induces pKa shifts on Fuberidazole. Fuberidazole significantly inhibits the growth of B. cinerea.

Fuberidazole (FBZ) (10 渭M) shows pKa shifts of 1.4 units in the present of CB8 (100 渭M)[1].
Fuberidazole (10-200 渭M; 72 h) exhibits an increasing growth inhibition rate on B. cinerea. And the CB7/CB8-bound Fuberidazole inhibits the growth of B. cinerea at least three times than Fuberidazole alone[1].

[1]. Saleh N, et al. Enhancement of in vitro fungicidal activity of fuberidazole to Botrytis cinerea by cucurbiturils. Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2014, 79: 301-309.

Chemical Properties of Fuberidazole

Cas No. 3878-19-1 SDF
Formula C11H8N2O M.Wt 184.194
溶解度 DMSO : 125 mg/mL (678.65 mM; ultrasonic and warming and heat to 60°C ) Storage
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Fuberidazole

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 5.4291 mL 27.1453 mL 54.2906 mL
5 mM 1.0858 mL 5.4291 mL 10.8581 mL
10 mM 542.9 μL 2.7145 mL 5.4291 mL
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In vivo Formulation Calculator (Clear solution) of Fuberidazole

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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