ML230 (Synonyms: CID44640177) |
| カタログ番号GC34672 |
ML230 (CID44640177; SID 88095709) は、ATP 結合カセット (ABC) トランスポーター ABCG2 の選択的阻害剤であり、ABCB1 よりも ABCG2 に対して 36 倍選択的であり、EC50 値はそれぞれ 0.13 μM および 4.65 μM です。
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Cas No.: 1776055-05-0
Sample solution is provided at 25 µL, 10mM.
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ML230 (CID44640177; SID 88095709) is a selective inhibitor of ATP-binding cassette (ABC) transporter ABCG2, and 36-fold selective for ABCG2 over ABCB1 with EC50s values of 0.13 μM and 4.65 μM, respectively[1]. EC50: ABCG2 (0.13 μM)[1]
[1]. Strouse JJ, et al. Selective Efflux Inhibition of ATP-binding Cassette Sub-family G Member 2. Probe Reports from the NIH Molecular Libraries Program. November 30, 2010.
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