POPSO |
| カタログ番号GC67472 |
POPSO は両性イオン緩衝液であり、浸透圧を高め、陰イオンのユニポートを著しく阻害します。 POPSO は 24 mM の IC50 値で塩化物ユニポートを阻害します。 POPSO は、藻類の銅の取り込みと毒性を高め、ミトコンドリア内膜を損ないます。 POPSOセスキナトリウム塩の使用pH範囲は7.2～8.5です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 68189-43-5
Sample solution is provided at 25 µL, 10mM.
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POPSO is a zwitterionic buffer, increases osmolality and shows marked inhibition of anion uniport. POPSO inhibits chloride uniport with an IC50 value of 24 mM. POPSO enhances copper uptake and toxicity in alga, impairs mitochondrial inner membrane. The working pH range of POPSO sesquisodium salt is 7.2-8.5[1][2][3].
[1]. Ng LT, et al. Effect of buffers and osmolality on anion uniport across the mitochondrial inner membrane. Biochim Biophys Acta. 1993 Jun 10;1143(1):29-37.
[2]. Vasconcelos, et al. Influence of zwitterionic pH buffers on the bioavailability and toxicity of copper to the alga Amphidinium carterae. 2009 Nov;19(10):2542-2550.
[3]. Kebede N, et al. Electrogenerated chemiluminescence of tris(2,2' bipyridine)ruthenium(II) using common biological buffers as co-reactant, pH buffer and supporting electrolyte. Analyst. 2015 Nov 7;140(21):7142-5.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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