16,16-dimethyl Prostaglandin A2 (Synonyms: 16,16dimethyl PGA2) |
| Catalog No.GC41942 |
16,16-dimethyl PGA2 is a metabolism-resistant analog of PGA2 with a prolonged in vivo half-life.
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Cas No.: 41691-92-3
Sample solution is provided at 25 µL, 10mM.
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16,16-dimethyl PGA2 is a metabolism-resistant analog of PGA2 with a prolonged in vivo half-life. It inhibits the proliferation of Sendai virus in cultured African green monkey kidney cells by >90% at a concentration of 4 µg/ml. Daily infusion of 10 µg of 16,16-dimethyl PGA2 methyl ester into mice infected with influenza A virus increased survival by 40%. Similar treatment of mice inoculated with erythroleukemia cells delayed tumor growth and increased survival time.
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