α-Methyl-DL-aspartic acid |
Catalog No.GC66189 |
α-Methyl-DL-aspartic acid는 argininosuccinate synthase (ASS)의 특정 억제제이며 1-citrulline을 1-arginine으로 재순환시키는 속도 제한 효소이기도 합니다.821d96072c2d58d8970e76f526b0f6b8
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Cas No.: 2792-66-7
Sample solution is provided at 25 µL, 10mM.
α-Methyl-DL-aspartic acid is a specific inhibitor of argininosuccinate synthase (ASS), and also is the rate-limiting enzyme for the recycling of 1-citrulline to 1-arginine[1].
α-methyl-dl-aspartic acid can significantly reduce the anti-hypertensive activity of Bj-BPP-10c in SHR[2].
α-methyl-dl-aspartic acid (147 mg/kg, i.v.) can diminish the l-citrulline-induced retinal vasodilation in Wistar rats[1].
Animal Model: | Wistar rats |
Dosage: | 147 mg/kg |
Administration: | 147 mg/kg, i.v. |
Result: | Attenuated the increase of retinal arteriolar diameter induced by L-citrulline. |
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