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Antifungal agent 49

Catalog No.GC71239 Copy One-Click Copy Product Info

Antifungal agent 49 (실시례 112)는 항진균제다.

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Antifungal agent 49 Chemical Structure

Cas No.: 1414861-21-4

Size 가격 재고 수량
1 mg
US$720.00
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고객 리뷰

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Description of Antifungal agent 49

Antifungal agent 49 (Example 112) is an antifungal agent. Antifungal agent 49 is active against Cryptococcus neoformans with a MIC value of 49 μM.

Antifungal agent 49 (Example 112) (48 h) shows cytotoxicity with a CC50 of 79 μM in HepDES 19 cells[1].

References:
[1]. Maureen J. DONLIN, et al. Anti-fungal compounds. Patent. WO2017184752. 2017-10-26.

Chemical Properties of Antifungal agent 49

Cas No. 1414861-21-4 SDF
Formula C15H12O4 M.Wt 256.25
Solubility DMSO : 25 mg/mL (97.56 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Storage 4°C, sealed storage, away from moisture and light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Antifungal agent 49

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.9024 mL 19.5122 mL 39.0244 mL
5 mM 780.5 μL 3.9024 mL 7.8049 mL
10 mM 390.2 μL 1.9512 mL 3.9024 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of Antifungal agent 49

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for Antifungal agent 49

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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