Atrial Natriuretic Peptide (3-28) (human) (trifluoroacetate salt) (Synonyms: ANP (3-28) (human)) |
| Catalog No.GC42872 |
Atrial natriuretic peptide (ANP) (3-28) is a synthetic and truncated form of ANP, which is an endogenous peptide generated by proteolysis of prepro-ANP that is secreted by cardiomyocytes in the heart.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Atrial natriuretic peptide (ANP) (3-28) is a synthetic and truncated form of ANP, which is an endogenous peptide generated by proteolysis of prepro-ANP that is secreted by cardiomyocytes in the heart. ANP (3-28) potently inhibits renin release from cultured renal juxtaglomerular cells (Ki = 10 pM) in a cGMP-dependent manner. It also dose-dependently decreases mean arterial pressure (MAP) and arterial plasma renin activity and increases fractional sodium and calcium excretion, urine volume, and glomerular filtration rate in conscious dogs with a maximum effect attained when administered at a dose of 200 pM. ANP (3-28) (human) is a 26 amino acid peptide corresponding to the truncated human protein sequence.
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