>>Signaling Pathways>> Metabolism>> Reproductive Biology>>17-Epiestriol

17-Epiestriol (Synonyms: 16α-hydroxy-17α-Estradiol, 16α,17α-Estriol, 17α-Estriol, 17-epi-Estriol, NSC 84051)

Catalog No.GC48819

A metabolite of estrone

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17-Epiestriol Chemical Structure

Cas No.: 1228-72-4

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1mg
US$163.00
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5mg
US$733.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

17-Epiestriol is a metabolite of estrone .1 It is formed from estrone via a 16α-hydroxy estrone intermediate by reduction of the C-17 ketone. 17-Epiestriol binds to estrogen receptor α (ERα) and ERβ with relative binding affinities of 29 and 80 compared with 17β-estradiol .2

1.Brinton, L.A., Trabert, B., Anderson, G.L., et al.Serum estrogens and estrogen metabolites and endometrial cancer risk among postmenopausal womenCancer Epidemiol. Biomarkers Prev.25(7)1081-1089(2016) 2.Kuiper, G.G.J.M., Lemmen, J.G., Carlsson, B., et al.Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor βEndocrinology139(10)4252-4263(1998)

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