Tecarfarin |
| Catalog No.GC38857 |
Tecarfarin(ATI-5923)은 경구 활성 및 비경쟁적 비타민 K 에폭사이드 환원효소(VKOR) 길항제이며 비타민 K 의존성 응고 인자 II, VII, IX 및 X의 활성화를 손상시킵니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 867257-26-9
Sample solution is provided at 25 µL, 10mM.
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Tecarfarin (ATI-5923) is an orally active and non-competitive vitamin K epoxide reductase (VKOR) antagonist, and impairs the activation of the vitamin K-dependent clotting factors II, VII, IX and X[1]. Tecarfarin has the antithrombotic activity [2].
[1]. Hobl EL, et al. Tecarfarin: A Novel Vitamin K Antagonist. Thromb Haemost. 2017 Nov;117(11):2009-2011. [2]. Bowersox SS, et al. Antithrombotic activity of the novel oral anticoagulant, Tecarfarin [Sodium 3-[4-((1,1,1,3,3,3-hexafluoro-2-methylpropan-2-yloxy) carbonyl) benzyl]-2-oxo-2H-chromen-4-olate] in animal models. Thromb Res. 2010 Nov;126(5):e383-8.
Average Rating: 5 (Based on Reviews and 17 reference(s) in Google Scholar.)
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