Tyk2-IN-9 |
Catalog No.GC39644 |
Tyk2-IN-9(화합물 26)는 TYK2-JH2 및 JAK1-JH2에 대해 IC50이 각각 0.076 및 1.8nM인 선택적 Tyk-2 억제제입니다.
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Cas No.: 2127109-85-5
Sample solution is provided at 25 µL, 10mM.
Tyk2-IN-9 is a potent,selective and specific inhibitor of JAK kinases, inhibits Tyk2, JAK1 and JAK2 with IC50 values of 6 nM, 21nM and 6nM, respectively. Tyk2-IN-9, example 19, is extracted from patent US2017240552A1[1].
[1]. Matthew Frank Brown, et al. Pyrazolo[1,5-a]pyrazin-4-yl derivatives. Patent US20170240552A1
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