>>Signaling Pathways>> Neuroscience>> Seizure Disorders>>3,4-Dihydroquinolin-2(1H)-one

3,4-Dihydroquinolin-2(1H)-one

Catalog No.GC46557

A building block

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3,4-Dihydroquinolin-2(1H)-one Chemical Structure

Cas No.: 553-03-7

Size 가격 재고 수량
1 g
US$47.00
재고 있음
5 g
US$168.00
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10 g
US$312.00
재고 있음
25 g
US$659.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

3,4-Dihydroquinolin-2(1H)-one is a building block.1,2 It has been used in the synthesis of compounds with antidepressant and anticonvulsant activities, as well as dual ligands of sigma (σ) receptors and the NMDA receptor GluN2b subunit that have antioxidant and neuroprotective properties.

1.Deng, X.-Q., Song, M.-X., Zheng, Y., et al.Design, synthesis and evaluation of the antidepressant and anticonvulsant activities of triazole-containing quinolinonesEur. J. Med. Chem.73217-224(2014) 2.Zampieri, D., Fortuna, S., Calabretti, A., et al.Discovery of new potent dual sigma receptor/GluN2b ligands with antioxidant property as neuroprotective agentsEur. J. Med. Chem.180268-282(2019)

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