Arachidonoyl Ethanolamide-d8 (Synonyms: AEAd8, Anandamided8)

Name: Arachidonoyl Ethanolamide-d8
Brand: GlpBio
SKU: GC46876
Availability: InStock
Rating: 5 (30 reviews)

Catalog No.GC46876

An internal standard for the quantification of arachidonoyl ethanolamide

Products are for research use only. Not for human use. We do not sell to patients.

Arachidonoyl Ethanolamide-d8 Chemical Structure

Cas No.: 924894-98-4

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100 μg	US$66.00	재고 있음
500 μg	US$294.00	재고 있음
1 mg	US$521.00	재고 있음
5 mg	US$2,278.00	재고 있음

Tel：(909) 407-4943 Email: sales@glpbio.com

고객 리뷰

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.

GlpBio Products Cited In Reputable Papers

Nature
610.7931 (2022): 366-372

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618, 1017–1023 (2023)

Cell
183.7 (2020): 1867-1883

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31, 1291–1307 (2021)

Cell Research
33, 273–287 (2023)

Cell Research
33, 546–561 (2023)

Molecular Cancer
21.1 (2022): 1-17

Molecular Cancer
21.1 (2022): 1-18

Cancer Cell
39 (2021): 1-16

Cell Host Microbe
30.8 (2022): 1124-1138

Cell Host Microbe
31.5 (2023): 766-780

Cell Host Microbe
31.3 (2023): 418-43

Cell Metabolism
34.2 (2022): 240-255

Ann Rheum Dis
82(4): 533-545 (2023)

Cell Mol Immunol
20, 264–276 (2023)

Adv Funct Mater
33.35 (2023): 2214998

Description Chemical Properties Product Documents

Product Documents

Quality Control & SDS

View current batch:

Purity: >99.00%

Arachidonoyl ethanolamide-d₈ (AEA-8) contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of AEA by GC- or LC-mass spectrometry. AEA is the ethanolamine amide of arachidonic acid, first isolated from porcine brain.¹ It is an endogenous cannabinoid neurotransmitter that binds to both CB₁ and CB₂ receptors.² AEA inhibits the specific binding of [³H]-HU-243 to synaptosomal membranes with a K_i value of 52 nM, compared to 46 nM for δ⁹-THC.¹

1.Devane, W.A., Hanus, L., Breuer, A., et al.Isolation and structure of a brain constituent that binds to the cannabinoid receptorScience258(5090)1946-1949(1992) 2.Felder, C.C., Briley, E.M., Axelrod, J., et al.Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transductionProc. Natl. Acad. Sci. U.S.A.90(16)7656-7660(1993)

Cas No.	924894-98-4	SDF
Synonyms	AEAd8, Anandamided8
Canonical SMILES	CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCO
Formula	C22H29D8NO2	M.Wt	355.6
Solubility	1 mg/ml EtOH:PBS pH 7.2: can dilute 1:1.6 (>380 μg/ml),10 mg/ml EtOH:PBS pH 7.2: can dilute 1:1 (>5 mg/ml)	Storage	Store at -20°C
General tips	Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition	Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
		1 mg	5 mg	10 mg
	1 mM	2.8121 mL	14.0607 mL	28.1215 mL
	5 mM	0.5624 mL	2.8121 mL	5.6243 mL
	10 mM	0.2812 mL	1.4061 mL	2.8121 mL

Molarity Calculator
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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal:μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Review for Arachidonoyl Ethanolamide-d8

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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Arachidonoyl Ethanolamide-d8 (Synonyms: AEAd8, Anandamided8)

고객 리뷰

GlpBio Citations

Bioactive Compounds Premium Provider

GlpBio Products Cited In Reputable Papers

Product Documents

Quality Control & SDS

Complete Stock Solution Preparation Table

Molarity Calculator

Dilution Calculator

In vivo Formulation Calculator (Clear solution)

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