C16 1-Deoxyceramide (m18:1/16:0) (Synonyms: C16:0 1-Deoxyceramide, C16:0 Ceramide (m18:1/16:0), Cer(m18:1/16:0), N-Hexadecanoyl-1-deoxy-4,5-dihydro-Sphingosine) |
| Catalog No.GC46975 |
A long-chain atypical ceramide
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1246298-56-5
Sample solution is provided at 25 µL, 10mM.
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C16 1-Deoxyceramide (m18:1/16:0) is a long-chain atypical ceramide containing a 1-deoxysphingosine (m18:1(4E)) backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 C16 1-Deoxyceramide (m18:1/16:0) has been found in RAW 264.7 cells.3
1.Steiner, R., Saied, E.M., Othman, A., et al.Elucidating the chemical structure of native 1-deoxysphingosineJ. Lipid Res.57(7)1194-1203(2016) 2.Alecu, I., Othman, A., Penno, A., et al.Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathwayJ. Lipid Res.58(1)60-71(2017) 3.JimÉnez-Rojo, N., Sot, J., Busto, J.V., et al.Biophysical properties of novel 1-deoxy-(dihydro)ceramides occurring in mammalian cellsBiophys. J.107(12)2850-2859(2014)
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