Prostaglandin E1 isopropyl ester (Synonyms: PGE1 isopropyl ester) |
| Catalog No.GC47990 |
An ester prodrug form of PGE1
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 217182-28-0
Sample solution is provided at 25 µL, 10mM.
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Prostaglandin E1 isopropyl ester is an ester prodrug form of prostaglandin E1 with enhanced lipid solubility.1,2 The ester functional group on PGE1 isopropyl ester is readily hydrolyzed in cells and in vivo to release active PGE1.1 PGE1 isopropyl ester exhibits a faster penetration flux than the free acid form of PGE1 when applied topically to isolated mouse skin. Topical administration of PGE1 isopropyl ester (1 mM) reduces fluid pressure within human dermal fibroblast cell aggregates.2
1.Ho, H.O., Hwang, M.C., Tseng, S.L., et al.The percutaneous penetration of prostaglandin E1 and its alkyl estersJ. Control Release58(3)349-355(1999) 2.Stuhr, L.E., Reith, A., LepsØe, S., et al.Fluid pressure in human dermal fibroblast aggregates measured with micropipettesAm. J. Physiol. Cell Physiol.285(5)C1101-1108(2003)
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