L-Alanine-d3 (Synonyms: 2-Aminopropanoic Acid-d3, α-Alanine-d3, L-(+)-Alanine-d3, (S)-Alanine-d3, (2S)-2-Azaniumylpropanoate-d3) |
| Catalog No.GC49373 |
L-알라닌-d3(L-2-아미노프로피온산-d3)은 L-알라닌으로 표지된 중수소입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 63546-27-0
Sample solution is provided at 25 µL, 10mM.
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L-Alanine-d3 is intended for use as an internal standard for the quantification of L-alanine by GC- or LC-MS. L-Alanine is a non-essential amino acid.1 It is produced by direct β-decarboxylation of L-aspartate by L-aspartate β-decarboxylase or transamination of pyruvate in the glucose-alanine cycle and is a precursor for gluconeogenesis.2 Dysregulation of L-alanine metabolism is associated with various disease states, including diabetes, metabolic syndrome, ketotic hypoglycemia, and acquired acute lactic acidosis.
1.Graber, R., Kasper, P., Malashkevich, V.N., et al.Conversion of aspartate aminotransferase into an L-aspartate β-decarboxylase by a triple active-site mutationJ. Biol. Chem.274(44)31203-31208(1999) 2.Felig, P.Progress in endocrinology and metabolism: The glucose-alanine cycleMetabolis.22(2)179-207(1973)
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