AGI-24512 |
Catalog No.GC33019 |
AGI-24512는 IC50이 8nM인 강력한 메티오닌 아데노실트랜스퍼라제 2α(MAT2A) 억제제입니다. AGI-24512는 DNA 손상 반응을 유발합니다. AGI-24512는 시험관 내에서 MTAP가 삭제된 암세포의 증식을 차단할 수 있습니다. AGI-24512는 항암 연구에 사용될 수 있습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2201066-53-5
Sample solution is provided at 25 µL, 10mM.
AGI-24512 is a methionine adenosyltransferase 2A (MATA2 ) inhibitors useful for treatment of cancer. AGI-24512 blocks growth of MTAP-deleted cancer cells in vitro.
[1]. Agios. Targeting MAT2A in MTAP-deleted Cancers. Presented at the American Association for Cancer Research (AACR) Annual Meeting, April 14-18, 2018, Chicago, IL, USA
Average Rating: 5
(Based on Reviews and 17 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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