- Cat.No. 상품명 정보
- GC43239 Chk2 Inhibitor Chk2 억제제(화합물 1)는 Chk2 및 Chk1에 대한 IC50이 각각 13.5nM 및 220.4nM인 체크포인트 키나제 2(Chk2)의 강력하고 선택적인 억제제입니다. Chk2 억제제는 강한 ATM(ataxia telangiectasia mutated) 의존성 Chk2 매개 방사선 보호 효과를 유발할 수 있습니다.
- GC49664 CB-1158 An arginase inhibitor
- GC48548 iBET-BD2 A BD2 bromodomain inhibitor
- GC48427 CAY10774 A PD-1/PD-L1 interaction inhibitor
- GC47741 Nalanthalide A fungal metabolite with potassium channel inhibitory and antiviral activities
- GC47533 L-778,123 A dual inhibitor of FTase and GGTase I
- GC47387 G6PDi-1 G6PDi-1은 IC50이 0.07μM인 가역적이고 비경쟁적인 포도당-6-인산 탈수소효소(G6PD) 억제제입니다.
- GC46895 Aurintricarboxylic Acid (ammonium salt) A protein synthesis inhibitor with diverse biological activities
- GC46549 2F-Peracetyl-Fucose 2F-Peracetyl-Fucose(1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos)는 강력한 푸코실트랜스퍼라제(FUT) 억제제로 작용합니다.
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GC18572
Concanavalin A
콘카나마이신 A는 Streptomyces diastatochromogenes에서 분리된 매크로라이드 항생물질인 콘카나마이신 가족에 속하며, 고도로 활성화되고 선택적으로 세포질 프로톤-ATPase (v-[H+]ATPase)를 억제하는 항생제입니다.
- GC46226 SS-208 SS-208은 IC50이 12nM인 선택적 HDAC6 억제제입니다. SS-208은 흑색종에서 항종양 활성을 가지고 있습니다.
- GC45966 LH1307 A PD-1/PD-L1 interaction inhibitor
- GC45771 LH1306 A PD-1/PD-L1 interaction inhibitor
- GC45515 MX1013 MX1013은 항아폽토시스 활성이 있는 강력하고 비가역적인 디펩티드 카스파제 억제제입니다. MX1013은 30nM의 IC50으로 재조합 인간 카스파제 3을 억제합니다.
- GC44919 SP 600125, negative control SP 600125 is a selective, cell-permeable, reversible inhibitor of JNK isoforms 1-3 with Ki values of 0.19 μM.
- GC44505 Oleyl Anilide AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol.
- GC43928 JJH260 JJH260 is an N-hydroxy hydantoin carbamate that inhibits androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs).
- GC43804 Halofuginone (hydrochloride) Halofuginone is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D.
- GC43307 Concanamycin B Concanamycin B is a macrolide antibiotic that selectively inhibits vacuolar type H+-ATPases, also known as V-ATPases (IC50 = 5 nM).
- GC42668 ABC34 ABC34 is an inactive control probe for JJH260, the inhibitor of androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs).
- GC42644 9-Deazaguanine 9-Deazaguanine is an analog of guanine that acts as an inhibitor of purine nucleoside phosphorylase (PNP; Kd = 160 nM).
- GC42112 2-Acetyl-5-tetrahydroxybutyl Imidazole Sphingosine-1-phosphate (S1P) lyase catalyzes the irreversible decomposition of S1P to hexadecanaldehyde and phosphoethanolamine.
- GC18716 Bisindolylmaleimide XI (hydrochloride) Bisindolylmaleimide XI(염산염)(Ro 32-0432)는 PKCα, PKCIIII, PKCβ, PKCIII에 대해 9 nM, 28 nM, 31 nM, 37 nM 및 108 nM의 IC50을 갖는 강력하고 선택적이고 경구 활성인 PKC 억제제입니다. , 각각.
- GC18443 Acetyl-6-formylpterin Acetyl-6-formylpterin is an inhibitor of mucosal-associated invariant T (MAIT) cell activation.